SCHEMBL3052012

SCHEMBL3052012

C=Cc1cccc2sc3ccccc3c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.48
SLC9A1 P19634 2/20 0.40
MAPT P10636 4/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.38
KMT2A Q03164 2/20 0.38
DUSP3 P51452 1/20 0.38
BLM P54132 1/20 0.38
PTPN5 P54829 1/20 0.38
PTPN11 Q06124 1/20 0.38
MCL1 Q07820 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321606 0.86 MAPT (0.47) GPR3SLC9A1MAPTMEN1POLB
SCHEMBL9526065 0.81 CYP2A6 (0.48) GPR3MAPTMEN1POLBKMT2A
SCHEMBL31672181 0.81 CYP2A6 (0.48) GPR3MAPTMEN1POLBKMT2A
SCHEMBL21791411 0.80 SLC9A1 (0.38) GPR3SLC9A1MAPTMEN1POLB
SCHEMBL25165146 0.78 GPR3 (0.45) GPR3MAPTMEN1POLBKMT2A
SCHEMBL4961400 0.78 GPR3 (0.54) GPR3MAPTMEN1POLBKMT2A
SCHEMBL3057151 0.77 GPR3 (0.48) GPR3SLC9A1MAPTMEN1KMT2A
SCHEMBL31192241 0.74 ALDH1A1 (0.46) MEN1KMT2ABLMTDP1ALDH1A1
SCHEMBL16180494 0.74 ALDH1A1 (0.46) MEN1KMT2ABLMTDP1ALDH1A1
SCHEMBL28536685 0.74 GPR3 (0.41) GPR3MAPTMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5252371-A Rewritable photochromic optical disk PIONEER ELECTRONIC CORPORATION (JP) 1993-10-12 US claimed
EP-0161005-B1 NOVEL SQUARIUM COMPOUNDS, PROCESS FOR PREPARING THE SAME AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS CONTAINING THE SAME FUJI XEROX CO., LTD. (JP) 1989-12-20 EP claimed
US-4626485-A Substituted squarium compounds, process for preparing the same and electrophotographic photoreceptors containing the same FUJI XEROX CO., LTD. (JP) 1986-12-02 US claimed
EP-0161005-A2 Novel squarium compounds, process for preparing the same and electrophotographic photoreceptors containing the same FUJI XEROX CO., LTD. (JP) 1985-11-13 EP claimed
JP-57046246-A None JP disclosed
EP-4313156-B1 DISULFIDE-BASED PRODRUG COMPOUNDS UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2025-08-06 EP disclosed
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-06-27 US disclosed
EP-4313156-A1 DISULFIDE-BASED PRODRUG COMPOUNDS Ludwig-Maximilians-Universität München (DE) 2024-02-07 EP disclosed
WO-2022200347-A1 DISULFIDE-BASED PRODRUG COMPOUNDS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2022-09-29 WO disclosed
US-20220077406-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-03-10 US disclosed
CN-110036047-A METHACRYLIC COPOLYMER AND MOLDED ARTICLE 株式会社可乐丽 2019-07-19 CN disclosed
US-8580403-B2 Organic light-emitting diode, display and illuminating device KABUSHIKI KAISHA TOSHIBA (JP) 2013-11-12 US disclosed
EP-0161005-A2 Novel squarium compounds, process for preparing the same and electrophotographic photoreceptors containing the same FUJI XEROX CO., LTD. (JP) 1985-11-13 EP disclosed
US-4451549-A Laminated photosensitive plate for electrophotography and process for preparation thereof MITA INDUSTRIAL CO., LTD. (JP) 1984-05-29 US disclosed
US-4349616-A HIGHLY PHOTOSENSITIVE TO SHORT WAVELENGTHS; COPIERS; REPRODUCTION;LIGHT-SENSITIVE ELEMENTS RICOH CO., LTD. (JP) 1982-09-14 US disclosed
US-4327168-A Electrophotographic element containing disazo pigment charge generating material RICOH CO., LTD. (JP) 1982-04-27 US disclosed
JP-S5746246-A ELECTROPHOTOGRAPHIC RECEPTOR RICOH CO LTD 1982-03-16 JP disclosed
US-4314016-A Electrophotographic element having a bisazo photoconductor RICOH CO., LTD. (JP) 1982-02-02 US disclosed
US-4260672-A Electrophotographic sensitive element having a photoconductive disazo pigment RICOH COMPANY, LTD. (JP) 1981-04-07 US disclosed
US-4250240-A Photosensitive material for use in electrophotography RICOH COMPANY, LTD. (JP) 1981-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND CBS, MSR1, P4HB GPR3 3182/4885SLC9A1 2705/4885MAPT 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.