Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22619921 | 0.78 | KDM4E (0.46) | KDM4ENAPRTALDH1A1FAAHHSD17B10 | |
| SCHEMBL31039846 | 0.78 | KDM4E (0.46) | KDM4ENAPRTALDH1A1FAAHHSD17B10 | |
| SCHEMBL17212191 | 0.78 | PIM1 (0.52) | PIM2PIM1HCAR2KDM4ENAPRT | |
| SCHEMBL30528355 | 0.76 | HSD17B10 (0.39) | PIM2PIM1KDM4ETERTALDH1A1 | |
| SCHEMBL370029 | 0.73 | ALDH1A1 (0.59) | PIM2PIM1HCAR2KDM4EALDH1A1 | |
| Bicarbonate SCHEMBL31484615 | 0.72 | HCAR2 (0.56) | PIM2PIM1HCAR2KDM4ENAPRT | |
| SCHEMBL29751844 | 0.71 | PIM2 (0.49) | PIM2PIM1HCAR2KDM4ENAPRT | |
| SCHEMBL18093529 | 0.71 | P4HA1 (0.61) | NAPRTALDH1A1FAAHHSD17B10CES1 | |
| SCHEMBL12571304 | 0.71 | PIM2 (0.49) | PIM2PIM1HCAR2KDM4ENAPRT | |
| SCHEMBL25098745 | 0.70 | MAPT (0.39) | PIM2PIM1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |