Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254239 | 0.91 | CTSK (0.55) | GNPATPAX8TDP1CTSSCTSK | |
| SCHEMBL7850315 | 0.91 | CTSK (0.62) | GNPATPAX8TDP1CTSSCTSK | |
| SCHEMBL20838286 | 0.90 | FOLH1 (0.57) | GNPATPAX8TDP1CTSSCTSK | |
| SCHEMBL20838288 | 0.90 | FOLH1 (0.57) | GNPATPAX8TDP1CTSSCTSK | |
| SCHEMBL22424958 | 0.90 | PAX8 (0.54) | GNPATPAX8TDP1CTSSCTSK | |
| SCHEMBL16908988 | 0.90 | ACE (0.59) | CA1CA2PAX8TDP1CTSS | |
| SCHEMBL13702233 | 0.90 | ACE (0.59) | CA1CA2PAX8TDP1CTSS | |
| SCHEMBL17039853 | 0.89 | FOLH1 (0.57) | PAX8TDP1CTSSCTSKCTSL | |
| SCHEMBL13956678 | 0.89 | PAX8 (0.52) | GNPATCA1CA2PAX8TDP1 | |
| SCHEMBL17254230 | 0.89 | PAX8 (0.53) | GNPATCA1CA2PAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576166-B2 | Contrast agents for detection of enzyme activities based on melanin synthesis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-03-17 | — | — | US | disclosed |
| US-20230248849-A1 | CONTRAST AGENTS FOR DETECTION OF ENZYME ACTIVITIES BASED ON MELANIN SYNTHESIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576166-B2 | Contrast agents for detection of enzyme activities based on melanin synthesis | TYR, MPO, LNPEP | GNPAT 1708/4885CA1 796/4885CA2 890/4885 |
| US-20230248849-A1 | CONTRAST AGENTS FOR DETECTION OF ENZYME ACTIVITIES BASED ON MELANIN SYNTHESIS | TYR, MPO, RNASE1 | GNPAT 1013/4885CA1 262/4885CA2 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.