Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 5/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281295 | 0.94 | GABRA1 (0.44) | RXRBRXRARXRGGABRA1GABRB2 | |
| SCHEMBL536261 | 0.94 | GABRA1 (0.44) | RXRBRXRARXRGGABRA1GABRB2 | |
| SCHEMBL305335 | 0.88 | ALDH1A1 (0.39) | HDAC1SMN1; SMN2TDP1ALDH1A1HPGD | |
| SCHEMBL907993 | 0.88 | GAA (0.39) | RXRBRXRARXRGGABRA1GABRB2 | |
| SCHEMBL4194148 | 0.82 | PTPN1 (0.36) | SMN1; SMN2TDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL16730170 | 0.82 | GABRA1 (0.35) | RXRBRXRARXRGGABRA1GABRB2 | |
| SCHEMBL4185138 | 0.82 | KIF11 (0.39) | RXRBRXRARXRGSMN1; SMN2ALDH1A1 | |
| SCHEMBL26059369 | 0.80 | ESR1 (0.48) | ALDH1A1HPGDHSD17B10LMNATYR | |
| SCHEMBL4459027 | 0.80 | LMNA (0.47) | HDAC6HDAC1SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL305401 | 0.80 | CYP3A4 (0.41) | RXRBRXRAALDH1A1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491773-B2 | Halogenated polymers with new sequence distributions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-02-17 | — | — | US | claimed |