Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097701 | 1.00 | NR3C2 (0.54) | NR3C2ALDH1A1MAPTPKLRGAA | |
| SCHEMBL30541719 | 0.83 | ALDH1A1 (0.63) | NR3C2ALDH1A1MAPTGAALMNA | |
| SCHEMBL21074864 | 0.83 | ALDH1A1 (0.63) | NR3C2ALDH1A1MAPTGAALMNA | |
| SCHEMBL21061872 | 0.82 | MGLL (0.59) | NR3C2ALDH1A1GAALMNAMGLL | |
| SCHEMBL30541708 | 0.82 | MGLL (0.59) | NR3C2ALDH1A1GAALMNAMGLL | |
| SCHEMBL21098096 | 0.80 | MGLL (0.57) | NR3C2ALDH1A1MAPTGAALMNA | |
| SCHEMBL30541689 | 0.79 | ALDH1A1 (0.54) | NR3C2ALDH1A1MAPTLMNAPARP1 | |
| SCHEMBL21061733 | 0.79 | ALDH1A1 (0.54) | NR3C2ALDH1A1MAPTLMNAPARP1 | |
| SCHEMBL21098290 | 0.79 | MGLL (0.50) | NR3C2ALDH1A1MAPTGAALMNA | |
| SCHEMBL14072961 | 0.79 | NR3C2 (0.61) | NR3C2ALDH1A1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183224-A1 | BEZOXAZINE DERIVATIVES USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183224-A1 | BEZOXAZINE DERIVATIVES USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | LPL, LIPC, PNLIP | NR3C2 2686/4885ALDH1A1 800/4885MAPT 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.