Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | LTA | P01374 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | RAD1 | O60671 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929894 | 0.80 | PTGS2 (0.47) | ALDH1A1MAPTCYP3A4TDP1LMNA | |
| SCHEMBL483832 | 0.80 | CA1 (0.70) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL4362606 | 0.80 | PTGS2 (0.47) | ALDH1A1MAPTCYP3A4TDP1LMNA | |
| SCHEMBL30543087 | 0.79 | CA1 (0.45) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL30543083 | 0.79 | CA1 (0.45) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL15563090 | 0.79 | CA1 (0.45) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL11574824 | 0.79 | TDP1 (0.42) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL25891586 | 0.78 | CA1 (0.50) | CA1CA2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL13997435 | 0.77 | GAA (0.61) | CA2ALDH1A1MAPTCYP3A4HPGD | |
| SCHEMBL25891612 | 0.77 | LMNA (0.40) | ALDH1A1MAPTKDM4EUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | NEUROPORE THERAPIES, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20150197513-A1 | ARYL- AND HETEROARYL-SUBSTITUTED BENZENE DERIVATIVES AS MODULATORS OF PI3-KINASE SIGNALLING PATHWAYS | NEUROPORE THERAPIES, INC. | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | TPMT, ABCB1, DPP8 | CA1 4486/4885CA2 3591/4885ALDH1A1 1945/4885 |
| US-20150197513-A1 | ARYL- AND HETEROARYL-SUBSTITUTED BENZENE DERIVATIVES AS MODULATORS OF PI3-KINASE SIGNALLING PATHWAYS | TFEB, ULK1, MTOR | CA1 4869/4885CA2 4301/4885ALDH1A1 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.