Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 6/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429484 | 0.86 | SCN8A (0.43) | TRPV1BRD4SCN9ASCN5ABACE1 | |
| SCHEMBL25428113 | 0.84 | TRPV1 (0.39) | TRPV1BRD4SCN9ASCN5A | |
| SCHEMBL30544026 | 0.84 | TRPV1 (0.39) | TRPV1BRD4SCN9ASCN5A | |
| SCHEMBL30544057 | 0.84 | SCN9A (0.44) | TRPV1BRD4SCN9ASCN5ABACE1 | |
| SCHEMBL25952320 | 0.84 | SCN9A (0.44) | TRPV1BRD4SCN9ASCN5ABACE1 | |
| SCHEMBL25429756 | 0.83 | ICMT (0.39) | TRPV1SCN9ASCN5ABACE1 | |
| SCHEMBL30544045 | 0.83 | ICMT (0.39) | TRPV1SCN9ASCN5ABACE1 | |
| SCHEMBL25954187 | 0.82 | GRIN2B (0.50) | TRPV1 | |
| SCHEMBL25429273 | 0.80 | NOD2 (0.37) | TRPV1SCN9ASCN5A | |
| SCHEMBL25429043 | 0.80 | SLC6A2 (0.38) | TRPV1BRD4SCN9AMCHR1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |