Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MARK3 | P27448 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896673 | 0.81 | TRPV3 (0.32) | — | |
| SCHEMBL29896626 | 0.79 | AR (0.33) | ALOX5APFEN1 | |
| SCHEMBL29899284 | 0.79 | ALOX5AP (0.31) | ALOX5APFEN1 | |
| SCHEMBL5612909 | 0.74 | — | — | |
| SCHEMBL5612891 | 0.72 | PBRM1 (0.47) | MAPK1 | |
| SCHEMBL29899235 | 0.70 | KIF11 (0.36) | ALOX5APFEN1 | |
| SCHEMBL17991849 | 0.70 | AR (0.33) | — | |
| SCHEMBL6167894 | 0.69 | — | — | |
| SCHEMBL31393744 | 0.69 | ALPL (0.43) | — | |
| SCHEMBL2820801 | 0.68 | IDO1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312362-B2 | Spiro derivatives of Alpha-D-galactopyranosides | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-27 | — | — | US | disclosed |
| US-12304902-B2 | Hydroxyheterocycloalkane-carbamoyl derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-20 | — | — | US | disclosed |
| US-12291520-B2 | Galectin-3 inhibiting 2-hydroxycycloalkane-1-carbamoyl derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-06 | — | — | US | disclosed |
| US-20240124427-A1 | HYDROXYHETEROCYCLOALKANE-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-04-18 | — | — | US | disclosed |
| US-20240109930-A1 | TRIAZOLYL-METHYL SUBSTITUTED ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-04-04 | — | — | US | disclosed |
| US-20230348442-A1 | GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-02 | — | — | US | disclosed |
| US-20230295182-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348442-A1 | GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | LGALS1, LGALS2, LGALS3 | ALOX5AP 3392/4885FEN1 3567/4885PLK4 3535/4885 |
| US-12291520-B2 | Galectin-3 inhibiting 2-hydroxycycloalkane-1-carbamoyl derivatives | LGALS1, LGALS2, LGALS3 | ALOX5AP 3392/4885FEN1 3567/4885PLK4 3535/4885 |
| US-12304902-B2 | Hydroxyheterocycloalkane-carbamoyl derivatives | LGALS1, LGALS3, LGALS2 | ALOX5AP 3266/4885FEN1 2303/4885PLK4 3909/4885 |
| US-12312362-B2 | Spiro derivatives of Alpha-D-galactopyranosides | LGALS1, LGALS3, LGALS2 | ALOX5AP 4333/4885FEN1 2641/4885PLK4 3282/4885 |
| US-20230295182-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | LGALS1, LGALS3, LGALS2 | ALOX5AP 4333/4885FEN1 2641/4885PLK4 3282/4885 |
| US-20240124427-A1 | HYDROXYHETEROCYCLOALKANE-CARBAMOYL DERIVATIVES | LGALS1, LGALS3, LGALS2 | ALOX5AP 3266/4885FEN1 2303/4885PLK4 3909/4885 |
| US-20240109930-A1 | TRIAZOLYL-METHYL SUBSTITUTED ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | LGALS3, LGALS1, LGALS2 | ALOX5AP 4186/4885FEN1 3306/4885PLK4 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.