Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544861 | 0.82 | MMP2 (0.46) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL30544866 | 0.79 | FOLH1 (0.37) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL34467661 | 0.78 | HPGD (0.35) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL31300264 | 0.76 | NOS1 (0.34) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL34467670 | 0.72 | TDP1 (0.42) | ALDH1A1NPSR1MAPTKDM4EMEN1 | |
| SCHEMBL30544854 | 0.71 | FOLH1 (0.51) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL43996 | 0.64 | FOLH1 (0.66) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL9875634 | 0.64 | FOLH1 (0.66) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL43995 | 0.64 | FOLH1 (0.66) | FOLH1CA1CA2SLC15A2MMP2 | |
| SCHEMBL9161774 | 0.63 | ERAP2 (0.49) | FOLH1CA1CA2ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496837-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | The Research Foundation for The State University of New York (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023178107-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-09-21 | — | — | WO | disclosed |