Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544861 | 0.85 | MMP2 (0.46) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL30544862 | 0.79 | FOLH1 (0.36) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL34467688 | 0.78 | NOS1 (0.35) | ALOX15 | |
| SCHEMBL31300252 | 0.75 | ARG1 (0.38) | ALOX15 | |
| SCHEMBL30544854 | 0.72 | FOLH1 (0.51) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL30544865 | 0.72 | SIRT2 (0.46) | FOLH1 | |
| SCHEMBL30544857 | 0.65 | MMP2 (0.46) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL10615102 | 0.65 | GRIN1 (0.55) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL30544860 | 0.63 | FOLH1 (0.47) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL30544859 | 0.63 | FOLH1 (0.47) | FOLH1MMP2MMP9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496837-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | The Research Foundation for The State University of New York (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023178107-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-09-21 | — | — | WO | disclosed |