SCHEMBL305503

SCHEMBL305503

CCC(N)[Si](Oc1ccc(Cl)cc1)(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.38
SCN4A P35499 2/20 0.38
SLC6A3 Q01959 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 2/20 0.37
ADRB2 P07550 1/20 0.36
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
AOC3 Q16853 1/20 0.34
POLB P06746 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305460 0.81 SCN4A (0.37) LTA4HSCN4ASLC6A3SLC6A2SLC6A4
SCHEMBL196746 0.70 CYP1A2 (0.37) LTA4HMAOBMAOACYP2D6CYP2C9
SCHEMBL5400910 0.67 CYP1A2 (0.39) MAOBMAOACYP2D6CYP2C9POLB
SCHEMBL197410 0.66 LMNA (0.42) LTA4HMAOBMAOACYP2D6CYP2C9
SCHEMBL19088418 0.66 L3MBTL1 (0.44) SLC6A4CYP2D6CYP2C9POLB
SCHEMBL198322 0.66 L3MBTL1 (0.41) SLC6A3SLC6A2SLC6A4ADRB2MAOB
SCHEMBL9191274 0.64 SIGMAR1 (0.49) CYP2C9POLB
SCHEMBL13123958 0.64 PPARA (0.41) SLC6A4CYP2D6CYP2C9POLB
SCHEMBL1977034 0.63 SLC6A4 (0.57) SCN4ASLC6A3SLC6A2SLC6A4ADRB2
SCHEMBL10879582 0.63 HPGD (0.41) MAOBMAOACYP2D6CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US claimed
EP-2173491-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2010-04-14 EP claimed
EP-2040847-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2009-04-01 EP claimed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO claimed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US claimed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
WO-2014066237-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-05-01 WO disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
US-8092686-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-01-10 US disclosed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US disclosed
US-7913852-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-03-29 US disclosed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO disclosed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US disclosed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO disclosed
EP-1838451-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC RESINS, INC. (US) 2007-10-03 EP disclosed
US-20070000839-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2007-01-04 US disclosed
US-20060151360-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2006-07-13 US disclosed
WO-2006071672-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2006-07-06 WO disclosed