Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.37 |
| ▸ | MGLL | Q99685 | 9/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325767 | 1.00 | ENPP2 (0.37) | ENPP2MGLLFAAHPREPPIK3CD | |
| SCHEMBL25324021 | 0.86 | MGLL (0.38) | ENPP2MGLLFAAH | |
| SCHEMBL30553187 | 0.85 | MGLL (0.44) | ENPP2MGLLPREP | |
| SCHEMBL25324758 | 0.85 | MGLL (0.44) | ENPP2MGLLPREP | |
| SCHEMBL25326458 | 0.84 | ENPP2 (0.42) | ENPP2MGLL | |
| SCHEMBL25324941 | 0.83 | GPR119 (0.36) | ENPP2FAAH | |
| SCHEMBL30553215 | 0.83 | LPL (0.38) | ENPP2MGLLFAAH | |
| SCHEMBL25325591 | 0.83 | LPL (0.38) | ENPP2MGLLFAAH | |
| SCHEMBL25324702 | 0.82 | MGLL (0.39) | ENPP2MGLLPREP | |
| SCHEMBL25325530 | 0.82 | PPARD (0.42) | MGLLPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |