Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835503 | 1.00 | LTA4H (0.52) | LTA4HKMT2AMEN1LMNANAPRT | |
| SCHEMBL1513017 | 0.84 | AKR1C3 (0.47) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL23458451 | 0.75 | NAPRT (0.59) | LTA4HKMT2AMEN1LMNANAPRT | |
| SCHEMBL29551348 | 0.72 | NAPRT (0.50) | NAPRTALDH1A1KDM4ECYP1A2TSHR | |
| SCHEMBL445478 | 0.72 | NAPRT (0.50) | NAPRTALDH1A1KDM4ECYP1A2TSHR | |
| SCHEMBL8801902 | 0.71 | LTA4H (0.61) | LTA4HKMT2AMEN1LMNANAPRT | |
| SCHEMBL447058 | 0.71 | ALDH1A1 (0.43) | NAPRTALDH1A1RAB9A | |
| SCHEMBL30934037 | 0.71 | ALDH1A1 (0.43) | NAPRTALDH1A1RAB9A | |
| SCHEMBL30506330 | 0.71 | SMN1; SMN2 (0.40) | KMT2AMEN1NAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL30641935 | 0.71 | DGAT1 (0.42) | KMT2AMEN1ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |