Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037143 | 0.86 | LTA4H (0.61) | LTA4HCES2CES1KMT2AHTT | |
| SCHEMBL8609990 | 0.85 | CES2 (0.63) | LTA4HCES2CES1KMT2AHTT | |
| SCHEMBL29880739 | 0.85 | CES2 (0.63) | LTA4HCES2CES1KMT2AHTT | |
| SCHEMBL10112157 | 0.83 | LMNA (0.58) | LTA4HKMT2AMEN1MAPTLMNA | |
| SCHEMBL7401884 | 0.83 | LTA4H (0.49) | LTA4HKMT2AHTTMEN1MAPT | |
| SCHEMBL16977349 | 0.82 | LTA4H (0.61) | LTA4HCES2CES1KMT2AHTT | |
| SCHEMBL29765677 | 0.81 | CES2 (0.59) | CES2CES1KMT2AMAPK14MEN1 | |
| SCHEMBL158348 | 0.81 | CES2 (0.59) | CES2CES1KMT2AMAPK14MEN1 | |
| SCHEMBL14431511 | 0.81 | CES2 (0.59) | CES2CES1KMT2AHTTMAPK14 | |
| SCHEMBL13291390 | 0.80 | CES2 (0.74) | CES2CES1KMT2AHTTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695751-B1 | AGENT ACTING ON THE CENTRAL NERVOUS SYSTEM, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VITA INVEST SA (ES) | 1997-03-26 | — | — | EP | disclosed |
| EP-0695751-A1 | AGENT ACTING ON THE CENTRAL NERVOUS SYSTEM, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VITA-INVEST, S.A. (ES) | 1996-02-07 | — | — | EP | disclosed |
| CN-86101906-A | Process for preparing 1, 2 benzisoxazol-3-yl and 1, 2 benzisothiazol-3-yl derivatives | — | 1986-10-01 | — | — | CN | disclosed |