Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AIP | O00170 | 1/20 | 0.38 |
| ▸ | SGTA | O43765 | 1/20 | 0.38 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.38 |
| ▸ | STIP1 | P31948 | 1/20 | 0.38 |
| ▸ | PPP5C | P53041 | 1/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.38 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364074 | 0.73 | KMT2A (0.53) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL3452499 | 0.68 | CYP1A2 (0.55) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10679034 | 0.68 | CYP1A2 (0.34) | CYP1A2ALDH1A1KDM4EHPGDFHIT | |
| SCHEMBL11344084 | 0.67 | IDO1 (0.33) | — | |
| SCHEMBL26784147 | 0.64 | ALDH1A1 (0.44) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12111485 | 0.62 | ALDH1A1 (0.58) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL5080674 | 0.61 | DAO (0.42) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL27888882 | 0.61 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL3451713 | 0.61 | ALDH1A1 (0.56) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL24525703 | 0.60 | ADRA2A (0.43) | ALDH1A1KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |