SCHEMBL30560977

SCHEMBL30560977

Cc1cccc(C=CC(N)=O)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.40
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
IAPP P10997 3/20 0.40
PTGER1 P34995 1/20 0.38
PTGER4 P35408 1/20 0.38
PTGER3 P43115 1/20 0.38
PTGER2 P43116 1/20 0.38
LMNA P02545 3/20 0.38
HPGD P15428 2/20 0.38
MAPT P10636 2/20 0.38
TRPA1 O75762 1/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 4/20 0.37
PELI1 Q96FA3 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NFE2L2 Q16236 3/20 0.37
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358892 0.85 ALDH1A1 (0.48) PTPN1CCNCCDK8LMNAHPGD
SCHEMBL30560932 0.85 ALDH1A1 (0.48) PTPN1CCNCCDK8LMNAHPGD
SCHEMBL1124329 0.85 ALDH1A1 (0.48) PTPN1CCNCCDK8LMNAHPGD
SCHEMBL1124331 0.85 ALDH1A1 (0.48) PTPN1CCNCCDK8LMNAHPGD
SCHEMBL17095076 0.84 CD44 (0.41) PTPN1CCNCCDK8IAPPPTGER1
SCHEMBL30560916 0.83 CA1 (0.53) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL690917 0.83 CA1 (0.53) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL691503 0.83 CA1 (0.53) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL8149990 0.82 PTGS2 (0.41) PTPN1CCNCCDK8IAPPLMNA
SCHEMBL8149994 0.82 PTGS2 (0.41) PTPN1CCNCCDK8IAPPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768792-B Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2024-10-18 CN disclosed
CN-116768792-A Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2023-09-19 CN disclosed