Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124329 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9ALMNAHPGD | |
| SCHEMBL1124331 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9ALMNAHPGD | |
| SCHEMBL28358892 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9ALMNAHPGD | |
| SCHEMBL2328371 | 0.85 | NFKB1 (0.50) | LMNAHTTPTPN1MAPTKDM4E | |
| SCHEMBL30560977 | 0.85 | PTPN1 (0.40) | ALDH1A1TSHRRAB9ALMNAHPGD | |
| SCHEMBL5598954 | 0.83 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAMAPT | |
| SCHEMBL5598952 | 0.83 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAMAPT | |
| SCHEMBL17095076 | 0.83 | CD44 (0.41) | ALDH1A1TSHRRAB9ALMNAHPGD | |
| SCHEMBL78556 | 0.82 | CA1 (0.62) | ALDH1A1TSHRRAB9ALMNAHTT | |
| SCHEMBL2425317 | 0.82 | CA1 (0.62) | ALDH1A1TSHRRAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768792-B | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-116768792-A | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2023-09-19 | — | — | CN | disclosed |