Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055485 | 0.85 | BDKRB1 (0.38) | POLBMEN1KMT2AMAPK14BDKRB1 | |
| SCHEMBL3059843 | 0.85 | BDKRB1 (0.39) | POLBMEN1KMT2ABDKRB1F10 | |
| SCHEMBL3042694 | 0.82 | CYP2D6 (0.45) | F10 | |
| SCHEMBL3052593 | 0.80 | HTR6 (0.38) | MAPK14BDKRB1F10HTR6 | |
| SCHEMBL3065820 | 0.78 | BDKRB1 (0.39) | POLBMEN1KMT2ABDKRB1MAPT | |
| SCHEMBL3053633 | 0.77 | KMO (0.46) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL13139524 | 0.77 | HTR6 (0.46) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL3058131 | 0.76 | BDKRB1 (0.38) | MEN1KMT2ABDKRB1MAPTF10 | |
| SCHEMBL3062814 | 0.75 | HTR6 (0.46) | MTNR1AMTNR1BBDKRB1HTR6 | |
| SCHEMBL3050887 | 0.74 | MTNR1A (0.40) | MTNR1AMTNR1BPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222324-A1 | Substituted Indole Compounds | GRUENENTHAL GMBH (DE) | 2010-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222324-A1 | Substituted Indole Compounds | BDKRB1, BDKRB2, EDNRB | MTNR1A 25/4885MTNR1B 6/4885POLB 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.