SCHEMBL3056752

SCHEMBL3056752

O=C1N=NC(c2ccccc2)=N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
ALDH1A1 P00352 5/20 0.38
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35
GAA P10253 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CFTR P13569 1/20 0.34
GOPC Q9HD26 1/20 0.34
PLA2G10 O15496 1/20 0.34
BTK Q06187 1/20 0.34
NOTUM Q6P988 2/20 0.33
KMT2A Q03164 2/20 0.33
GFER P55789 1/20 0.33
CYP1A2 P05177 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4877279 0.76 ALDH1A1 (0.38) MAPTALDH1A1RAB9ANPC1MAPK1
SCHEMBL8542761 0.76 MAOA (0.45) MAPTLMNAALDH1A1KDM4EHPGD
SCHEMBL8390215 0.73 KIF11 (0.45) NOTUMBACE1
SCHEMBL11771549 0.71 ALDH1A1 (0.32) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL21151453 0.70 ALDH1A1 (0.53) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL541879 0.70 C1R (0.37) MAPTLMNAHTTRAB9ANPC1
SCHEMBL4633787 0.67 MAPT (0.44) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL8656886 0.67 MAPT (0.40) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL643335 0.65 MAPT (0.37) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL1326009 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181156-A Hederagenin derivative and application thereof in preparation of anti-tumor drugs 延边大学 2022-10-14 CN claimed
US-10847410-B2 Ruthenium-containing semiconductor structure and method of manufacturing the same TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-11-24 US claimed
US-20200090983-A1 SEMICONDUCTOR STRUCTURE AND METHOD OF MANUFACTURING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-03-19 US claimed
US-20070060028-A1 CMP SLURRY DELIVERY SYSTEM AND METHOD OF MIXING SLURRY THEREOF UNITED MICROELECTRONICS CORP. (TW) 2007-03-15 US claimed
US-20060191871-A1 CMP SLURRY DELIVERY SYSTEM AND METHOD OF MIXING SLURRY THEREOF UNITED MICROELECTRONICS CORP. (TW) 2006-08-31 US claimed
CN-118955602-A Celastrol split heterocyclic derivative and application thereof 延边大学 2024-11-15 CN disclosed
US-11756825-B2 Semiconductor structure with oxidized ruthenium TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2023-09-12 US disclosed
US-20210098283-A1 SEMICONDUCTOR STRUCTURE AND METHOD OF MANUFACTURING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2021-04-01 US disclosed
US-10847410-B2 Ruthenium-containing semiconductor structure and method of manufacturing the same TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-11-24 US disclosed
US-20200090983-A1 SEMICONDUCTOR STRUCTURE AND METHOD OF MANUFACTURING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-03-19 US disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-4946856-A 5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants MERRELL DOW PHARMACEUTICALS INC. (US) 1990-08-07 US disclosed
US-4946856-A 5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants MERRELL DOW PHARMACEUTICALS INC. (US) 1990-08-07 US disclosed