Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568926 | 0.83 | PIK3CD (0.53) | IDO1TP53 | |
| SCHEMBL30568920 | 0.83 | TDO2 (0.51) | IDO1TP53 | |
| SCHEMBL29892464 | 0.82 | CYP1A2 (0.54) | KDM4EHPGDNPSR1RXFP1NT5E | |
| SCHEMBL19503242 | 0.76 | HTT (0.49) | KDM4EHPGDNPSR1RXFP1NT5E | |
| SCHEMBL31168142 | 0.76 | HTT (0.49) | KDM4EHPGDNPSR1RXFP1NT5E | |
| SCHEMBL30568954 | 0.74 | PIK3CA (0.58) | KDM4ENT5EPDGFRBPDGFRAMAPK1 | |
| SCHEMBL30568937 | 0.74 | TDO2 (0.53) | KDM4EPDGFRBPDGFRALMNAMAPK1 | |
| SCHEMBL5362363 | 0.74 | ESR1 (0.52) | ESR2BACE1 | |
| SCHEMBL5255693 | 0.74 | TRPA1 (0.57) | ESR2ALOX5APFEN1PDK2BACE1 | |
| SCHEMBL30568875 | 0.73 | NPC1 (0.59) | KDM4ENT5EBACE1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110740991-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2023-07-04 | — | — | CN | disclosed |