Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | NMT1 | P30419 | 4/20 | 0.56 |
| ▸ | NMT2 | O60551 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470811 | 1.00 | MAOB (0.60) | MAOBMEN1KMT2AHSP90AA1NMT1 | |
| SCHEMBL24471022 | 0.85 | MAOB (0.66) | MAOBMEN1KMT2ACASP3SENP8 | |
| SCHEMBL23117661 | 0.82 | CASP3 (0.52) | MAOBMEN1KMT2ACASP3SENP8 | |
| SCHEMBL28561390 | 0.81 | GPBAR1 (0.48) | MAOBMEN1KMT2AHSP90AA1NMT1 | |
| SCHEMBL4792619 | 0.81 | ALDH1A1 (0.68) | MAOBMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL7950720 | 0.81 | MAOB (0.79) | MAOBMEN1KMT2ACASP3SENP8 | |
| SCHEMBL30254805 | 0.80 | GPBAR1 (0.62) | MAOBNMT1NMT2 | |
| SCHEMBL28564336 | 0.80 | GPBAR1 (0.62) | MAOBNMT1NMT2 | |
| SCHEMBL7956495 | 0.80 | MAOB (0.79) | MAOBMEN1KMT2ACASP3SENP8 | |
| SCHEMBL717067 | 0.79 | KDM4E (0.62) | MAOBMEN1KMT2ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |