Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | RIOK2 | Q9BVS4 | 10/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | FECH | P22830 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572694 | 0.91 | RET (0.45) | RETRIOK2CHRNB2CHRNA4MTOR | |
| SCHEMBL19462890 | 0.78 | RET (0.45) | RETNCF1TGFBR1ACVR1KIT | |
| SCHEMBL19459259 | 0.74 | LIPG (0.43) | RETNCF1TGFBR1ACVR1KIT | |
| SCHEMBL19481688 | 0.74 | RET (0.54) | RET | |
| SCHEMBL24615598 | 0.73 | JAK1 (0.42) | RETJAK2JAK1TYK2JAK3 | |
| SCHEMBL19482443 | 0.72 | RET (0.41) | RETNCF1TGFBR1ACVR1KIT | |
| SCHEMBL21679774 | 0.72 | KHK (0.43) | RETTGFBR1ACVR1KIT | |
| SCHEMBL19481736 | 0.72 | RET (0.51) | RETACVR1 | |
| SCHEMBL19459081 | 0.72 | RET (0.41) | RETNCF1TGFBR1ACVR1KIT | |
| SCHEMBL19486469 | 0.71 | BMP4 (0.46) | RETTGFBR1ACVR1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165581-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-09-07 | — | — | WO | disclosed |