Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.44 |
| ▸ | ITGAL | P20701 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576102 | 0.88 | RXRA (0.49) | RXRAALDH1A1CYP1A2TP53NPC1 | |
| SCHEMBL30576180 | 0.84 | POLB (0.47) | RXRAALDH1A1MAPK13MAPK12MAPK11 | |
| SCHEMBL30576091 | 0.82 | BRAF (0.53) | RXRAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30576093 | 0.79 | RXRA (0.46) | RXRAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30576073 | 0.79 | RAB9A (0.56) | RXRAALDH1A1MAPK14RAB9AHTR1A | |
| SCHEMBL30576056 | 0.78 | F2 (0.49) | RXRAALDH1A1MAPK13MAPK12MAPK11 | |
| SCHEMBL30576138 | 0.78 | NPC1 (0.51) | MAPK14TP53NPC1RAB9AHTR1A | |
| SCHEMBL30576126 | 0.77 | MAPT (0.48) | RXRAALDH1A1ITGB2ICAM1ITGAL | |
| SCHEMBL30576064 | 0.77 | ITGB2 (0.49) | L3MBTL1ITGB2ICAM1ITGALGSK3B | |
| SCHEMBL30894579 | 0.76 | RXRA (0.80) | RXRAALDH1A1MAPK14ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |