Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576030 | 0.88 | RXRA (0.49) | RXRATP53GSK3BRAB9ANPC1 | |
| SCHEMBL30576093 | 0.83 | RXRA (0.46) | RXRAEGFRGSK3B | |
| SCHEMBL30576180 | 0.80 | POLB (0.47) | RXRASMN1; SMN2GSK3BRAB9ANPC1 | |
| SCHEMBL30576073 | 0.79 | RAB9A (0.56) | RXRASMN1; SMN2EGFRGSK3BRAB9A | |
| SCHEMBL30576091 | 0.78 | BRAF (0.53) | RXRAKMT2AEGFRGSK3BRAB9A | |
| SCHEMBL30576126 | 0.77 | MAPT (0.48) | RXRASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30894579 | 0.76 | RXRA (0.80) | RXRAKMT2ASMN1; SMN2TP53EGFR | |
| SCHEMBL30576056 | 0.76 | F2 (0.49) | RXRAMEN1KMT2ATP53CCNA2 | |
| SCHEMBL30576138 | 0.76 | NPC1 (0.51) | MEN1KMT2ASMN1; SMN2TP53CCNA2 | |
| SCHEMBL30643224 | 0.74 | CCNA2 (0.59) | LMNASMN1; SMN2TP53GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |