Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 6/20 | 0.47 |
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.46 |
| ▸ | ITGAL | P20701 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576117 | 0.91 | RAF1 (0.48) | MAPTRAF1BRAFBTKRXRA | |
| SCHEMBL30576073 | 0.89 | RAB9A (0.56) | MAPTRXRASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL30576180 | 0.88 | POLB (0.47) | RXRASMN1; SMN2ALDH1A1RAB9AHTR1F | |
| SCHEMBL30576056 | 0.84 | F2 (0.49) | MAPTITGB2ICAM1ITGALRXRA | |
| SCHEMBL30576093 | 0.83 | RXRA (0.46) | MAPTBRAFRXRA | |
| SCHEMBL30576069 | 0.83 | NPC1 (0.57) | MAPTRXRASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL30576091 | 0.80 | BRAF (0.53) | BRAFRXRARAB9AHTR1F | |
| SCHEMBL30576044 | 0.80 | HTR1F (0.57) | RXRASMN1; SMN2ALDH1A1RAB9AHTR1F | |
| SCHEMBL30576121 | 0.80 | MAPK14 (0.52) | MAPTRXRARAB9AHTR1F | |
| SCHEMBL29083757 | 0.78 | RXRA (0.60) | ITGB2ICAM1ITGALRXRAMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |