Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.45 |
| ▸ | WNT1 | P04628 | 8/20 | 0.45 |
| ▸ | GSK3B | P49841 | 6/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 3/20 | 0.44 |
| ▸ | CLK3 | P49761 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576093 | 0.90 | RXRA (0.46) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576020 | 0.88 | MAPK14 (0.47) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576067 | 0.87 | MALT1 (0.49) | DYRK1AWNT1GSK3BMAPK14CLK2 | |
| SCHEMBL30576121 | 0.87 | MAPK14 (0.52) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576044 | 0.85 | HTR1F (0.57) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576117 | 0.83 | RAF1 (0.48) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576128 | 0.83 | MAPT (0.55) | DYRK1AGSK3BMAPK14PIP5K1CMAPT | |
| SCHEMBL30576180 | 0.78 | POLB (0.47) | RXRADYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576073 | 0.75 | RAB9A (0.56) | RXRADYRK1AGSK3BMAPK14CLK2 | |
| SCHEMBL30576091 | 0.75 | BRAF (0.53) | RXRADYRK1AWNT1GSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |