Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.44 |
| ▸ | WNT1 | P04628 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576020 | 0.91 | MAPK14 (0.47) | MAPK14DYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30576044 | 0.87 | HTR1F (0.57) | MAPK14SMN1; SMN2DYRK1AWNT1GSK3B | |
| SCHEMBL30576035 | 0.87 | RXRA (0.46) | MAPK14DYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30576121 | 0.85 | MAPK14 (0.52) | MAPK14DYRK1AWNT1GSK3BHTR1F | |
| SCHEMBL30576117 | 0.83 | RAF1 (0.48) | MAPK14SMN1; SMN2DYRK1AWNT1GSK3B | |
| SCHEMBL30576128 | 0.81 | MAPT (0.55) | MAPK14DYRK1AGSK3B | |
| SCHEMBL30576073 | 0.78 | RAB9A (0.56) | MAPK14SMN1; SMN2DYRK1AGSK3BHTR1F | |
| SCHEMBL30576093 | 0.78 | RXRA (0.46) | MAPK14DYRK1AWNT1GSK3BBRAF | |
| SCHEMBL30576180 | 0.77 | POLB (0.47) | MAPK14SMN1; SMN2DYRK1AWNT1GSK3B | |
| SCHEMBL29083757 | 0.75 | RXRA (0.60) | MAPK14SMN1; SMN2DYRK1AGSK3BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |