Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | ITGAL | P20701 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576073 | 0.89 | RAB9A (0.56) | RXRARAB9AALDH1A1SMN1; SMN2HTR1F | |
| SCHEMBL30576044 | 0.88 | HTR1F (0.57) | RXRARAB9AALDH1A1SMN1; SMN2HTR1F | |
| SCHEMBL29083767 | 0.87 | RXRA (0.58) | RXRARAB9AALDH1A1MAPK14ITGB2 | |
| SCHEMBL30576135 | 0.82 | DYRK1A (0.55) | RAB9AALDH1A1SMN1; SMN2HTR1FEGFR | |
| SCHEMBL30576107 | 0.80 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2HTR1FEGFR | |
| SCHEMBL30366740 | 0.80 | RXRA (0.58) | RXRAMAPK14ITGB2ICAM1ITGAL | |
| SCHEMBL30576180 | 0.79 | POLB (0.47) | RXRARAB9AALDH1A1SMN1; SMN2HTR1F | |
| SCHEMBL30576121 | 0.79 | MAPK14 (0.52) | RXRARAB9AHTR1FMAPK14GSK3B | |
| SCHEMBL30576126 | 0.78 | MAPT (0.48) | RXRARAB9AALDH1A1SMN1; SMN2HTR1F | |
| SCHEMBL30576117 | 0.78 | RAF1 (0.48) | RXRAALDH1A1SMN1; SMN2HTR1FMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |