Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1125455 | 0.89 | HDAC8 (0.49) | MLYCDHDAC8GPBAR1TRPM8CTSS | |
| SCHEMBL8575500 | 0.80 | LMNA (0.49) | MLYCDGPBAR1MAOBEPHX2SMN1; SMN2 | |
| SCHEMBL4026691 | 0.79 | CES2 (0.55) | MLYCDTRPM8KAT6ASMN1; SMN2CES2 | |
| SCHEMBL29699666 | 0.79 | TAS2R14 (0.46) | MLYCDHDAC8GPBAR1CTSSMAOB | |
| SCHEMBL15761208 | 0.79 | TAS2R14 (0.46) | MLYCDHDAC8GPBAR1CTSSMAOB | |
| SCHEMBL4027267 | 0.78 | KAT6A (0.41) | MLYCDGPBAR1TRPM8KAT6ALPAR5 | |
| SCHEMBL21132665 | 0.77 | PDK2 (0.41) | HDAC8CTSSTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3688705 | 0.76 | CYP11B1 (0.48) | MLYCDTRPM8KAT6ACES2CES1 | |
| SCHEMBL2285021 | 0.76 | HPGD (0.40) | MLYCDTRPM8MAOBCLK1DYRK1A | |
| SCHEMBL17064947 | 0.76 | ALDH1A1 (0.43) | MLYCDTRPM8MAOBCLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655625-A | Compounds as SOS1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |