Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 5/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | PRKCG | P05129 | 3/20 | 0.43 |
| ▸ | PRKCB | P05771 | 3/20 | 0.43 |
| ▸ | PRKCH | P24723 | 3/20 | 0.43 |
| ▸ | PRKCI | P41743 | 3/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | PRKACG | P22612 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786152 | 0.80 | PARP1 (0.58) | PARP1ROCK2PRKCAPARP2CHEK1 | |
| SCHEMBL14498911 | 0.78 | ROCK2 (0.55) | PARP1ROCK2PRKCACHEK1CDK4 | |
| SCHEMBL14980870 | 0.77 | PARP1 (1.00) | PARP1PRKCACHEK1CDK4CCND1 | |
| SCHEMBL14169516 | 0.71 | PARP1 (0.71) | PARP1PARP2HSD17B10 | |
| SCHEMBL29202281 | 0.71 | PARP1 (0.62) | PARP1ROCK2PRKCACHEK1CDK4 | |
| SCHEMBL5438544 | 0.70 | PRKCA (0.71) | PARP1ROCK2PRKCACHEK1CDK4 | |
| SCHEMBL29202288 | 0.68 | PARP1 (0.61) | PARP1ROCK2PRKCACHEK1CDK4 | |
| SCHEMBL8317372 | 0.67 | PRKCA (1.00) | ROCK2PRKCACHEK1CDK4CCND1 | |
| SCHEMBL12846280 | 0.66 | PARP1 (0.60) | PARP1ROCK2PRKCACHEK1CDK4 | |
| SCHEMBL12786188 | 0.66 | PARP1 (0.86) | PARP1PARP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | LANTERN PHARMA INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-11759524-B2 | Mitochondrially targeted PARP inhibitor, and uses thereof | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | PARP1, PARP2, PARP3 | PARP1 1/4885ROCK2 2057/4885PRKCA 786/4885 |
| US-11759524-B2 | Mitochondrially targeted PARP inhibitor, and uses thereof | PARP1, PARP2, PARP3 | PARP1 1/4885ROCK2 1032/4885PRKCA 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.