Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.46 |
| ▸ | HTR3A | P46098 | 11/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | HTR5A | P47898 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30580494 | 0.85 | BRD4 (0.41) | HTR1AHTR3ASLC6A4CYP1A2CYP2C9 | |
| SCHEMBL795222 | 0.81 | TSHR (0.50) | HTR1ASLC6A4HRH1ALDH1A1GAA | |
| SCHEMBL14712741 | 0.79 | SLC6A9 (0.48) | HTR1AHTR3ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL30580496 | 0.78 | ALDH1A1 (0.47) | HTR1AHTR3AALDH1A1GAABRD4 | |
| SCHEMBL14176624 | 0.78 | HTR1A (0.43) | HTR1AHTR3ASLC6A4ALDH1A1GAA | |
| SCHEMBL13057071 | 0.77 | HTR1A (0.57) | HTR1AHTR3ASLC6A4CYP1A2ADRB2 | |
| SCHEMBL19086332 | 0.76 | LTA4H (0.47) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9557329 | 0.76 | ALDH1A1 (0.53) | HTR1AHTR3ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL8484975 | 0.76 | NTRK1 (0.48) | HTR1AHTR3ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30580506 | 0.76 | GAA (0.39) | SLC6A4CYP1A2CYP2C9HRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621745-A | (2-phenoxyphenyl) phenyl thioether compound and synthesis method thereof | 华北水利水电大学 | 2023-08-22 | — | — | CN | disclosed |