Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 12/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819001 | 0.78 | LMNA (0.46) | ALDH1A1 | |
| SCHEMBL3053874 | 0.78 | ALDH1A1 (0.52) | ALDH1A1BACE1 | |
| Hydrochloric Acid SCHEMBL4736859 | 0.78 | LMNA (0.46) | ALDH1A1 | |
| SCHEMBL3067561 | 0.78 | AADAT (0.46) | ALDH1A1AADATBACE1P2RX7 | |
| SCHEMBL3064281 | 0.78 | AADAT (0.46) | ALDH1A1AADATBACE1P2RX7 | |
| SCHEMBL3058822 | 0.74 | AADAT (0.54) | ALDH1A1AADATBACE1 | |
| SCHEMBL3060083 | 0.72 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL15665322 | 0.72 | FKBP1A (0.60) | ALDH1A1AADAT | |
| SCHEMBL15665896 | 0.72 | FKBP1A (0.60) | ALDH1A1AADAT | |
| Hydrochloric Acid SCHEMBL4736862 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | claimed |
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | claimed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | ALDH1A1 957/4885AADAT 3680/4885TP53 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.