SCHEMBL30584943

SCHEMBL30584943

COc1ccccc1-c1noc(N2CCC(C(=O)NCc3cccnc3)CC2)n1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ POLB P06746 1/20 0.53
▸ NPC1 O15118 1/20 0.53
▸ ALDH1A1 P00352 3/20 0.52
▸ TSHR P16473 3/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ LMNA P02545 3/20 0.50
▸ MAPT P10636 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25432654 1.00 KMT2A (0.54) KMT2ATDP1POLBNPC1ALDH1A1
SCHEMBL30584837 0.85 LMNA (0.62) KMT2AALDH1A1LMNAMAPTMEN1
SCHEMBL25438262 0.85 LMNA (0.62) KMT2AALDH1A1LMNAMAPTMEN1
SCHEMBL30584862 0.83 TSHR (0.59) KMT2ATDP1ALDH1A1TSHRCYP2C9
SCHEMBL30584903 0.83 ALDH1A1 (0.56) KMT2AALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL31546349 0.81 ALDH1A1 (0.54) KMT2AALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL25434291 0.81 HTT (0.60) KMT2AALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL31546388 0.81 HTT (0.60) KMT2AALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL25402378 0.79 MAPT (0.55) KMT2APOLBNPC1ALDH1A1TSHR
SCHEMBL30584799 0.77 CCR5 (0.52) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 KMT2A 1404/4885TDP1 3354/4885POLB 1664/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 KMT2A 1404/4885TDP1 3354/4885POLB 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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