Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078398 | 0.88 | ALDH1A1 (0.62) | HTR7HTR1AHPGDALOX15TDP1 | |
| SCHEMBL30585256 | 0.87 | L3MBTL1 (0.65) | HTR7HTR1AHPGDALOX15TDP1 | |
| SCHEMBL3895887 | 0.83 | L3MBTL1 (0.55) | HPGDALOX15TDP1KMT2APOLB | |
| SCHEMBL30585254 | 0.80 | BCHE (0.49) | HTR7HTR1ACA1CA2CA7 | |
| SCHEMBL31232857 | 0.79 | ALDH1A1 (0.67) | ALOX15SIGMAR1ALDH1A1KDM4ETSHR | |
| SCHEMBL4067173 | 0.78 | HPGD (1.00) | HPGDALOX15TDP1KMT2APOLB | |
| SCHEMBL29078387 | 0.77 | SMN1; SMN2 (0.57) | HTR7HTR1AKMT2APOLBSMN1; SMN2 | |
| SCHEMBL12150889 | 0.76 | KMT2A (0.76) | HTR7HTR1AHRH1KMT2ACA1 | |
| SCHEMBL10576036 | 0.76 | ALDH1A1 (0.81) | HTR7HPGDKMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL2313255 | 0.76 | KDM4E (0.67) | KMT2ASIGMAR1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |