Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585263 | 0.88 | SIGMAR1 (0.50) | ACHESIGMAR1HTR7HTR1A | |
| SCHEMBL30585267 | 0.87 | L3MBTL1 (0.52) | BCHEACHEKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30585245 | 0.84 | L3MBTL1 (0.56) | ACHESIGMAR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29078397 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1HTR1AL3MBTL1CA1 | |
| SCHEMBL31232857 | 0.80 | ALDH1A1 (0.67) | SIGMAR1KDM4EALDH1A1L3MBTL1CXCR4 | |
| SCHEMBL30585244 | 0.80 | HTR7 (0.73) | BCHEACHESIGMAR1HTR7KDM4E | |
| SCHEMBL2313255 | 0.77 | KDM4E (0.67) | SIGMAR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29078398 | 0.77 | ALDH1A1 (0.62) | BCHEACHESIGMAR1HTR7KDM4E | |
| SCHEMBL30585250 | 0.76 | LMNA (0.54) | ALDH1A1HTR1AL3MBTL1POLB | |
| SCHEMBL7625894 | 0.72 | HTR7 (0.67) | BCHEACHESIGMAR1HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |