Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930524 | 1.00 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1137437 | 0.85 | MAPT (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL21802324 | 0.81 | MAPT (0.41) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL30911319 | 0.81 | MAPT (0.41) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL15616481 | 0.78 | PDE5A (0.42) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1329600 | 0.77 | MEN1 (0.56) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5643188 | 0.76 | PDE10A (0.48) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL12967781 | 0.76 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1330570 | 0.75 | MAPT (0.52) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8600733 | 0.75 | PTGS2 (0.42) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119317622-A | Compounds useful as TYK2 inhibitors, preparation method and application thereof in medicine | 上海致根医药科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-116693449-A | Compounds useful as TYK2 inhibitors, preparation method and application thereof in medicine | 上海致根医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |