Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15616481 | 0.90 | PDE5A (0.42) | PTGS2HASPINKMT2AMEN1LMNA | |
| SCHEMBL8596095 | 0.81 | GPR84 (0.41) | PTGS2GPR84HASPINKMT2AMEN1 | |
| SCHEMBL8597530 | 0.77 | MEN1 (0.58) | GPR84KMT2AMEN1LMNAGAA | |
| SCHEMBL8602056 | 0.77 | LMNA (0.40) | KMT2AMEN1LMNAGAATHRB | |
| SCHEMBL28331495 | 0.76 | MEN1 (0.57) | GPR84KMT2AMEN1LMNAGAA | |
| SCHEMBL1347642 | 0.76 | PTGS2 (0.49) | PTGS2CYSLTR2CYSLTR1KMT2AMEN1 | |
| SCHEMBL4822817 | 0.75 | GPR84 (0.45) | PTGS2GPR84CYSLTR2CYSLTR1MAPT | |
| SCHEMBL8601055 | 0.75 | MAPT (0.39) | GPR84HASPINKMT2AMEN1GAA | |
| SCHEMBL24930524 | 0.75 | L3MBTL1 (0.47) | KMT2AMEN1LMNAGAATHRB | |
| SCHEMBL30586325 | 0.75 | L3MBTL1 (0.47) | KMT2AMEN1LMNAGAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |