SCHEMBL30596265

SCHEMBL30596265

CCOc1nc(Cl)cc2c1cnn2CCO

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 9/20 0.71
PDE4B Q07343 3/20 0.71
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CNR2 P34972 1/20 0.38
ATM Q13315 1/20 0.37
FSCN1 Q16658 1/20 0.33
PDE1A P54750 1/20 0.32
PDE1B Q01064 1/20 0.32
PDE1C Q14123 1/20 0.32
BCDIN3D Q7Z5W3 1/20 0.31
CYP1A2 P05177 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KMO O15229 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596249 0.82 PDE4D (0.77) PDE4DPDE4BKMT2AMEN1CNR2
SCHEMBL30596254 0.79 PDE4D (1.00) PDE4DPDE4BKMT2AMEN1CNR2
SCHEMBL30596260 0.74 PDE4D (0.86) PDE4DPDE4BKMT2AMEN1ATM
SCHEMBL30596261 0.73 PDE4D (0.59) PDE4DPDE4BKMT2AMEN1KMO
SCHEMBL30596272 0.73 PDE4D (0.59) PDE4DPDE4BKMT2AMEN1PDE1A
SCHEMBL30596250 0.71 PDE4D (1.00) PDE4DPDE4BPDE1APDE1BPDE1C
SCHEMBL30596266 0.69 PDE4D (0.49) PDE4DPDE4BKMT2AMEN1CYP1A2
SCHEMBL29950317 0.66 PDE4D (0.44) PDE4DPDE4BKMT2APDE1APDE1B
SCHEMBL16505774 0.66 PDE4D (0.44) PDE4DPDE4BKMT2APDE1APDE1B
SCHEMBL24402263 0.66 PDE4D (0.43) PDE4DPDE4BKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836162-A Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof 南方医科大学 2023-10-03 CN disclosed