Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596249 | 0.87 | PDE4D (0.77) | PDE4DPDE4BNPC1RAB9ATP53 | |
| SCHEMBL30596265 | 0.79 | PDE4D (0.71) | PDE4DPDE4BCNR2MEN1KMT2A | |
| SCHEMBL30596272 | 0.73 | PDE4D (0.59) | PDE4DPDE4BNPC1RAB9AMEN1 | |
| SCHEMBL30596261 | 0.73 | PDE4D (0.59) | PDE4DPDE4BMEN1KMT2APOLB | |
| SCHEMBL30596250 | 0.69 | PDE4D (1.00) | PDE4DPDE4B | |
| SCHEMBL30596266 | 0.64 | PDE4D (0.49) | PDE4DPDE4BNPC1RAB9AMEN1 | |
| SCHEMBL30596271 | 0.63 | PDE4D (0.78) | PDE4DPDE4BPOLB | |
| SCHEMBL16965743 | 0.63 | PDE4D (0.47) | PDE4DPDE4BRAB9AKMT2AMAPT | |
| SCHEMBL16505774 | 0.62 | PDE4D (0.44) | PDE4DPDE4BKMT2A | |
| SCHEMBL29950317 | 0.62 | PDE4D (0.44) | PDE4DPDE4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |