Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.59 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596261 | 0.88 | PDE4D (0.59) | PDE4DPDE4BKMOKMT2AMEN1 | |
| SCHEMBL30596249 | 0.78 | PDE4D (0.77) | PDE4DPDE4BKMOKMT2AMEN1 | |
| SCHEMBL30596264 | 0.76 | PDE4D (0.61) | PDE4DPDE4BKMT2AMEN1ALDH1A1 | |
| SCHEMBL30596254 | 0.73 | PDE4D (1.00) | PDE4DPDE4BKMOKMT2AMEN1 | |
| SCHEMBL30596265 | 0.73 | PDE4D (0.71) | PDE4DPDE4BKMOKMT2AMEN1 | |
| SCHEMBL30596251 | 0.69 | PDE4D (0.61) | PDE4DPDE4BKMT2AMEN1ALDH1A1 | |
| SCHEMBL30596250 | 0.68 | PDE4D (1.00) | PDE4DPDE4BPDE1APDE1BPDE1C | |
| SCHEMBL16965743 | 0.66 | PDE4D (0.47) | PDE4DPDE4BKMT2AALDH1A1KDM4E | |
| SCHEMBL30596271 | 0.66 | PDE4D (0.78) | PDE4DPDE4BALDH1A1KDM4EGAA | |
| SCHEMBL16505936 | 0.63 | PDE1C (0.38) | PDE4DKMOKMT2AKDM4EPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |