Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 8/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.75 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596254 | 0.87 | PDE4D (1.00) | PDE4DPDE4BKMOPOLBMEN1 | |
| SCHEMBL30596265 | 0.82 | PDE4D (0.71) | PDE4DPDE4BKMOMEN1KMT2A | |
| SCHEMBL30596272 | 0.78 | PDE4D (0.59) | PDE4DPDE4BKMOKDM4EMEN1 | |
| SCHEMBL30596261 | 0.78 | PDE4D (0.59) | PDE4DPDE4BKMOKDM4EPOLB | |
| SCHEMBL30596271 | 0.72 | PDE4D (0.78) | PDE4DPDE4BKDM4EPOLBS1PR2 | |
| SCHEMBL30596250 | 0.69 | PDE4D (1.00) | PDE4DPDE4B | |
| SCHEMBL16965743 | 0.68 | PDE4D (0.47) | PDE4DPDE4BKDM4EHPGDKMT2A | |
| SCHEMBL30596266 | 0.67 | PDE4D (0.49) | PDE4DPDE4BKDM4EHPGDHSD17B10 | |
| SCHEMBL13115663 | 0.66 | KMO (0.51) | PDE4DPDE4BKMOKDM4EHPGD | |
| SCHEMBL16505774 | 0.65 | PDE4D (0.44) | PDE4DPDE4BKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |