Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596272 | 0.88 | PDE4D (0.59) | PDE4DPDE4BKDM4EKMOMEN1 | |
| SCHEMBL30596249 | 0.78 | PDE4D (0.77) | PDE4DPDE4BKDM4EKMOMEN1 | |
| SCHEMBL30596251 | 0.76 | PDE4D (0.61) | PDE4DPDE4BKDM4EMEN1KMT2A | |
| SCHEMBL30596254 | 0.73 | PDE4D (1.00) | PDE4DPDE4BKMOMEN1KMT2A | |
| SCHEMBL30596265 | 0.73 | PDE4D (0.71) | PDE4DPDE4BKMOMEN1KMT2A | |
| SCHEMBL30596264 | 0.69 | PDE4D (0.61) | PDE4DPDE4BKDM4EMAPK1MEN1 | |
| SCHEMBL30596250 | 0.68 | PDE4D (1.00) | PDE4DPDE4B | |
| SCHEMBL30596266 | 0.68 | PDE4D (0.49) | PDE4DPDE4BKDM4ELMNAMEN1 | |
| SCHEMBL1199027 | 0.66 | ALDH1A1 (0.48) | KDM4ELMNAMEN1KMT2AGAA | |
| SCHEMBL16965743 | 0.66 | PDE4D (0.47) | PDE4DPDE4BKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |