Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596268 | 0.83 | NPBWR1 (0.48) | NPBWR1MCHR1USP7TSHRHTT | |
| SCHEMBL30596270 | 0.75 | PDE4D (0.50) | PDE4DPDE4BTSHRMAPTALDH1A1 | |
| SCHEMBL26525969 | 0.72 | ALDH1A1 (0.48) | NPBWR1MCHR1USP7TSHRHTT | |
| SCHEMBL15622855 | 0.69 | SMO (0.49) | NPBWR1MCHR1USP7TSHRHTT | |
| SCHEMBL30596265 | 0.69 | PDE4D (0.71) | PDE4DPDE4BSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL839950 | 0.69 | SLC2A1 (0.60) | HTTSMN1; SMN2CYP17A1CYP1A2MAPT | |
| SCHEMBL304075 | 0.69 | NR3C1 (0.50) | NPBWR1MCHR1USP7TSHRHTT | |
| SCHEMBL29638526 | 0.68 | PLK1 (0.40) | NPBWR1MCHR1TSHRHTTSMN1; SMN2 | |
| SCHEMBL30596261 | 0.68 | PDE4D (0.59) | PDE4DPDE4BPOLBLMNAKDM4E | |
| SCHEMBL30596249 | 0.67 | PDE4D (0.77) | PDE4DPDE4BHPGDPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |