Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596266 | 0.83 | PDE4D (0.49) | NPBWR1MCHR1USP7SMN1; SMN2TSHR | |
| SCHEMBL1355429 | 0.75 | SMN1; SMN2 (0.51) | NPBWR1MCHR1SMN1; SMN2TSHRHTT | |
| SCHEMBL15622855 | 0.75 | SMO (0.49) | NPBWR1MCHR1USP7SMN1; SMN2TSHR | |
| SCHEMBL839950 | 0.74 | SLC2A1 (0.60) | SMN1; SMN2HTTLMNACYP17A1CYP1A2 | |
| SCHEMBL304075 | 0.74 | NR3C1 (0.50) | NPBWR1MCHR1USP7SMN1; SMN2TSHR | |
| SCHEMBL30639303 | 0.73 | HTR3E (0.43) | TSHRHTTLMNAMAPTNPC1 | |
| SCHEMBL29096496 | 0.73 | HTR3E (0.43) | TSHRHTTLMNAMAPTNPC1 | |
| SCHEMBL26525969 | 0.73 | ALDH1A1 (0.48) | NPBWR1MCHR1USP7SMN1; SMN2TSHR | |
| SCHEMBL16014472 | 0.71 | PDE1A (0.50) | NPBWR1MCHR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL60445 | 0.71 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRHTTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |