SCHEMBL3059633

SCHEMBL3059633

C=CC(=O)Nc1cccc2ccc(S)cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
FYN P06241 1/20 0.42
SRC P12931 1/20 0.42
TRPV1 Q8NER1 11/20 0.42
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
TGM2 P21980 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PLAU P00749 1/20 0.40
NPC1 O15118 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711890 1.00 MAOA (0.44) MAOAMAOBPTPN1PTPN11FYN
SCHEMBL29591698 0.81 KDM4E (0.62) MAOAMAOBPTPN1PTPN11FYN
SCHEMBL647157 0.81 KDM4E (0.62) MAOAMAOBPTPN1PTPN11FYN
SCHEMBL766960 0.80 KDM4E (0.55) MAOAMAOBPTPN1PTPN11FYN
SCHEMBL30379721 0.74 PTPN1 (0.48) PTPN1PTPN11FYNSRCCYP2C9
SCHEMBL19999171 0.74 ALDH1A1 (0.64) PTPN1PTPN11FYNSRCKDM4E
SCHEMBL24150456 0.73 BCL2L1 (0.53) PTPN1PTPN11FYNSRC
SCHEMBL24149992 0.72 PTPN1 (0.45) PTPN1PTPN11FYNSRCMAPT
SCHEMBL18993427 0.71 TGM2 (0.65) TGM2
SCHEMBL613090 0.71 TGM2 (0.65) PTPN1PTPN11KDM4ETGM2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105885203-A Mildew-proof antibacterial EVA (ethylene-vinyl acetate) or PEVA (polyethylene vinyl acetate) film 东莞市开源塑化科技有限公司 2016-08-24 CN claimed
EP-3296327-B1 METHOD FOR PRODUCING ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS INC (JP) 2024-05-15 EP disclosed
CN-112105651-B Method for producing disk-shaped polymer particles 日清纺控股株式会社 2023-03-21 CN disclosed
CN-110325173-B Skin cosmetic 日清纺控股株式会社 2022-06-14 CN disclosed
US-11225541-B2 Production method for disc-shaped polymer particles NISSHINBO HOLDINGS INC. (JP) 2022-01-18 US disclosed
US-20210246250-A1 PRODUCTION METHOD FOR DISC-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS INC. (JP) 2021-08-12 US disclosed
EP-3792287-A1 PRODUCTION METHOD FOR DISC-SHAPED POLYMER PARTICLES Nisshinbo Holdings Inc. (JP) 2021-03-17 EP disclosed
CN-112105651-A Method for producing disk-shaped polymer particles 日清纺控股株式会社 2020-12-18 CN disclosed
CN-107531811-B Flat, oval polymer particles and use thereof 日清纺控股株式会社 2020-12-18 CN disclosed
US-10729623-B2 Method for producing elliptical, needle-shaped, or rod-shaped polymer particles NISSHINBO HOLDINGS, INC. (JP) 2020-08-04 US disclosed
US-20060188577-A1 Element having bioactive substance fixed thereto NISSHINBO INDUSTRIES, INC. (JP) 2006-08-24 US disclosed
US-20060052549-A1 Flat particles and process for production thereof NISSHINBO INDUSTRIES, INC. (JP) 2006-03-09 US disclosed
EP-1617219-A1 ELEMENT HAVING BIOACTIVE SUBSTANCE FIXED THERETO Nisshinbo Industries, Inc. (JP) 2006-01-18 EP disclosed
US-20050271875-A1 Composite particle with a carbodimide resin layer and process for producing the same NISSHINBO INDUSTRIES, INC. (JP) 2005-12-08 US disclosed
EP-1553124-A1 FLAKY PARTICLES AND PROCESS FOR PRODUCTION THEREOF Nisshinbo Industries, Inc. (JP) 2005-07-13 EP disclosed
US-20050118424-A1 particles comprising thermoplastic resins impregnated with carbodiimide compounds, having heat and solvent resistance, used as curing agents, stabilizers, hardeners, adhesives, coatings, paints, reinforcements and in automobiles, electronics, furniture, construction materials and as spacers TAKAHASHI IKUO (JP) 2005-06-02 US disclosed
EP-1528077-A1 COMPOSITE PARTICLE HAVING CARBODIIMIDE RESIN LAYER AND PROCESS FOR PRODUCING THE SAME Nisshinbo Industries, Inc. (JP) 2005-05-04 EP disclosed
US-6866934-B2 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2005-03-15 US disclosed
US-20030215636-A1 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2003-11-20 US disclosed
EP-1344795-A2 Carbodiimide-containing hardening type reactive particles, process for producing the same, and use of the same NISSHINBO INDUSTRIES, INC. (JP) 2003-09-17 EP disclosed