SCHEMBL3060069

SCHEMBL3060069

O=C1NC(=O)C(N=N[Ni])C(=O)N1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15411912 0.81 TSHR (0.36) TSHR
SCHEMBL7619815 0.81 TSHR (0.36) TSHR
SCHEMBL3126277 0.81 TSHR (0.36) TSHR
SCHEMBL15411908 0.79 TSHR (0.35) TSHR
SCHEMBL8647881 0.73 TSHR (0.38) TSHR
SCHEMBL20387031 0.70 TSHR (0.36) TSHR
SCHEMBL9613343 0.69 TSHR (0.35) TSHR
SCHEMBL3980936 0.63 KDM4E (0.38) TSHR
Ammonia Solution, Strong SCHEMBL2904283 0.62 KDM4E (0.36) TSHR
SCHEMBL11373401 0.58 HSD17B10 (0.50) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2161307-B1 Chinacridones containing fluoride in colour filters for LCD LANXESS DEUTSCHLAND GMBH (DE) 2012-08-29 EP claimed
CN-114381140-A Pigment preparation, method for the production thereof and use thereof 朗盛德国有限责任公司 2022-04-22 CN disclosed
EP-3981840-A1 PIGMENT PREPARATIONS CONTAINING DERIVATIVES OF AZOBARBITURIC ACID AND OF MELAMINE LANXESS Deutschland GmbH (DE) 2022-04-13 EP disclosed
US-10059844-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2018-08-28 US disclosed
US-10023744-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2018-07-17 US disclosed
US-10017644-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2018-07-10 US disclosed
US-10017645-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2018-07-10 US disclosed
US-10005909-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2018-06-26 US disclosed
US-20170275465-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-09-28 US disclosed
US-20170275464-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-09-28 US disclosed
US-20170275468-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-09-28 US disclosed
US-20170275467-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-09-28 US disclosed
US-20170275466-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-09-28 US disclosed
US-9663660-B2 Metal azo pigments LANXESS DEUTSCHLAND GMBH (DE) 2017-05-30 US disclosed
US-20160280923-A1 METAL AZO PIGMENTS LANXESS DEUTSCHLAND GMBH (DE) 2016-09-29 US disclosed
US-8512823-B2 Process for preparing metal compounds of an azo compound in the presence of seed crystals LANXESS DEUTSCHLAND GMBH (DE) 2013-08-20 US disclosed
US-8323357-B2 Fluorine-substituted perylenes for colour filters in LCDS LANXESS DEUTSCHLAND GMBH (DE) 2012-12-04 US disclosed
US-20100264382-A1 FLUORINE-SUBSTITUTED PERYLENES FOR COLOUR FILTERS IN LCDS LANXESS DEUTSCHLAND GMBH (DE) 2010-10-21 US disclosed
US-20100092887-A1 FLUORINE-CONTAINING QUINACRIDONES IN COLOUR FILTERS FOR LCDs LANXESS DEUTSCHLAND GMBH (DE) 2010-04-15 US disclosed
US-20070020409-A1 Process for preparing metal compounds of an azo compound in the presence of seed crystals LANXESS DEUTSCHLAND GMBH 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100264382-A1 FLUORINE-SUBSTITUTED PERYLENES FOR COLOUR FILTERS IN LCDS NRAS, GSDMD, HRAS TSHR 3305/4885
US-20070020409-A1 Process for preparing metal compounds of an azo compound in the presence of seed crystals MAPT, APC, TTR TSHR 3969/4885
US-20100092887-A1 FLUORINE-CONTAINING QUINACRIDONES IN COLOUR FILTERS FOR LCDs NDUFS2, NDUFS3, NDUFS4 TSHR 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.