Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731287 | 0.90 | GABRA1 (0.54) | S100A4TRPV1MAPTACHEGABRP | |
| SCHEMBL14906924 | 0.90 | S100A4 (0.56) | S100A4TRPV1ERN1MAPTACHE | |
| SCHEMBL5321726 | 0.88 | S100A4 (0.54) | S100A4TRPV1ERN1MAPTACHE | |
| Hydrogen Sulfide SCHEMBL10764626 | 0.86 | S100A4 (0.49) | S100A4TRPV1MAPTACHEGABRP | |
| SCHEMBL29430733 | 0.85 | ALDH1A1 (0.61) | S100A4TRPV1MAPTACHEGABRP | |
| SCHEMBL100456 | 0.85 | ALDH1A1 (0.61) | S100A4TRPV1MAPTACHEGABRP | |
| SCHEMBL205073 | 0.84 | S100A4 (0.51) | S100A4TRPV1MAPTPKMMAPK1 | |
| SCHEMBL28815409 | 0.84 | S100A4 (0.48) | S100A4TRPV1ERN1MAPTACHE | |
| SCHEMBL30949585 | 0.84 | S100A4 (0.48) | S100A4TRPV1MAPTACHEGABRP | |
| SCHEMBL1561802 | 0.84 | TSHR (0.56) | S100A4TRPV1ERN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119822366-A | High-heat-conductivity radiation heat dissipation graphite film and preparation method thereof | 青岛京湖新材料有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-118084682-A | Tetraphenylenediamine monomer containing trifluoromethyl and preparation method and application thereof | 株洲时代新材料科技股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117211072-A | Preparation method of in-situ growth nitro functional microporous organic network solid-phase microextraction fiber coating | 河北大学 | 2023-12-12 | — | — | CN | claimed |
| US-20070099905-A1 | Combinations of drugs for the treatment of neoplasms | BORISY ALEXIS | 2007-05-03 | — | — | US | claimed |
| EP-1651211-A4 | COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX INC (US) | 2006-11-22 | — | — | EP | claimed |
| EP-1651211-A2 | COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS | Combinatorx, Incorporated (US) | 2006-05-03 | — | — | EP | claimed |
| EP-1545544-A2 | COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | Combinatorx, Incorporated (US) | 2005-06-29 | — | — | EP | claimed |
| US-20050080075-A1 | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms | COMBINATORX, INC. | 2005-04-14 | — | — | US | claimed |
| WO-2005020913-A2 | FORMULATIONS, CONJUGATES, AND COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050054708-A1 | Combinations of drugs for the treatment of neoplasms | COMINATORX, INCORPORATED | 2005-03-10 | — | — | US | claimed |
| WO-2005011572-A2 | COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2005-02-10 | — | — | WO | claimed |
| US-20040116407-A1 | Combinations of drugs for the treatment of neoplasms | COMBINATORX, INC. | 2004-06-17 | — | — | US | claimed |
| WO-2004006842-A2 | COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2004-01-22 | — | — | WO | claimed |
| WO-2004006849-A2 | COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2004-01-22 | — | — | WO | claimed |
| CN-119822366-A | High-heat-conductivity radiation heat dissipation graphite film and preparation method thereof | 青岛京湖新材料有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-12179173-B2 | Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction | UNIVERSITY OF SOUTH FLORIDA (US) | 2024-12-31 | — | — | US | disclosed |
| CN-118084682-A | Tetraphenylenediamine monomer containing trifluoromethyl and preparation method and application thereof | 株洲时代新材料科技股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-0831813-A1 | METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040117-A1 | METHODS OF TREATING MICROBIAL INFECTIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040114-A1 | METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080075-A1 | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms | ABCB1, SLCO1B3, SLCO1B1 | S100A4 1239/4885TRPV1 2803/4885ERN1 4862/4885 |
| US-20070099905-A1 | Combinations of drugs for the treatment of neoplasms | VHL, NRAS, MYC | S100A4 64/4885TRPV1 3480/4885ERN1 4001/4885 |
| US-20050054708-A1 | Combinations of drugs for the treatment of neoplasms | TYMP, DPYD, DHFR | S100A4 471/4885TRPV1 4419/4885ERN1 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.