Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223570 | 0.90 | ASPH (0.39) | ASPHKDM8GAAMGAMAMY1A | |
| SCHEMBL30749266 | 0.90 | ASPH (0.39) | ASPHKDM8GAAMGAMAMY1A | |
| SCHEMBL30749339 | 0.86 | JAK2 (0.43) | GAAALOX15POLBKDM4EJAK2 | |
| SCHEMBL27223438 | 0.86 | JAK2 (0.43) | GAAALOX15POLBKDM4EJAK2 | |
| SCHEMBL17782060 | 0.86 | GAA (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30601258 | 0.86 | GAA (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27224143 | 0.86 | TSHR (0.38) | ASPHKDM8GAAALOX15TSHR | |
| SCHEMBL27224082 | 0.82 | JAK2 (0.46) | ALOX15KDM4EJAK2JAK1JAK3 | |
| SCHEMBL30749250 | 0.82 | JAK2 (0.46) | ALOX15KDM4EJAK2JAK1JAK3 | |
| SCHEMBL27224058 | 0.82 | ALDH1A1 (0.39) | ALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |