Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223570 | 1.00 | ASPH (0.39) | ASPHKDM8ALDH1A1KMT2AKDM4E | |
| SCHEMBL30601271 | 0.90 | ASPH (0.44) | ASPHKDM8ALDH1A1KDM4EGAA | |
| SCHEMBL27224143 | 0.90 | TSHR (0.38) | ASPHKDM8ALDH1A1KMT2AKDM4E | |
| SCHEMBL30749339 | 0.88 | JAK2 (0.43) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL27223438 | 0.88 | JAK2 (0.43) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL27224134 | 0.85 | ALOX15 (0.38) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL27224058 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL27224168 | 0.82 | ALOX15 (0.39) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL30601258 | 0.81 | GAA (0.39) | ALDH1A1KMT2AKDM4ETDP1MEN1 | |
| SCHEMBL17782060 | 0.81 | GAA (0.39) | ALDH1A1KMT2AKDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |