Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | EPX | P11678 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601967 | 0.77 | CHRNB2 (0.51) | — | |
| SCHEMBL31090403 | 0.75 | CHRNA7 (0.47) | ALDH1A1LTA4H | |
| SCHEMBL1920453 | 0.74 | RAB9A (0.54) | MPOTPOEPXLPONPC1 | |
| SCHEMBL4156883 | 0.74 | RAB9A (0.54) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23634063 | 0.74 | NCF1 (0.47) | MPOTPOEPXLPONPC1 | |
| SCHEMBL360929 | 0.70 | TDP1 (0.56) | MPOTPOEPXLPONPC1 | |
| SCHEMBL31538780 | 0.70 | NR5A1 (0.53) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3333555 | 0.70 | NOS3 (0.42) | MPOTPOEPXLPONCF1 | |
| SCHEMBL30261608 | 0.70 | MPO (0.34) | MPOTPOEPXLPONCF1 | |
| SCHEMBL23634060 | 0.69 | NCF1 (0.56) | MPOTPOEPXLPONCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179022-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | SHANGHAI ZHIGEN PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| EP-4488268-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | Shanghai Zhigen Pharmaceutical & Technology Co. Ltd. (CN) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023165574-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海致根医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179022-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | TYK2, WEE2, WEE1 | MPO 4512/4885TPO 1229/4885EPX 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.